|
KMID : 0613820230330040363
|
|
Journal of Life Science
2023 Volume.33 No. 4 p.363 ~ p.370
|
|
|
Biological Effects of C. tricuspidata Extract in Normal Rodents
|
|
Hwang Mi-Sun
Choi Ji-Yeon
Kim Kang-Min
Song Il-Dae
|
|
|
Abstract
|
|
|
|
In order to use Cudrania tricuspidata extract for the development of health-functional food, biological changes in normal rodents, such as changes in blood constituent cells, blood lipids, and anti-inflammatory activity, were measured after the rodents had been drinking the substance for 2 weeks. A 30 mg daily dose of the extract taken for 2 weeks produced no change in body weight or renal function, and no toxicity was observed. Increased red blood cell levels and white blood cell levels were confirmed, and platelet counts tended to increase; thus, the extract seems to cause an overall increase in blood cells. In the case of blood lipids, it was confirmed that the extract-treated group exhibited an effect of improved blood-lipid levels, demonstrated through an increase in HDL-C of 21%, with a decrease in triglyceride of 27% compared to the control group. In addition, the decreases in both GOT and GPT led to improved liver function through use of the extract. Therefore, this study suggests that drinking Cudrania tricuspidata extract can have various effects, such as promoting blood cell production, improving blood lipids profile, improving liver function, and improving inflammatory action. The extract would be useful in the future in developing high-value industrial products such as functional foods and pharmaceuticals.
|
|
|
KEYWORD
|
|
|
Biological activity, Cudrania tricuspidata, extract, functional food, normal rodent
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|